======Deep Vein Thrombosis====== =====Therapy===== * Initial anticoagulation: immediately for up to 10 days * Long-term anticoagulation: minimum of 3 months, sometimes 6-12 months; occasional indefinitely * Options * Heparin * LWMH * SubQ * DoAC * Apixaban * Recurrence: 3 per 100 person-years * Major bleed: 3 per 100 person-years * peak-to-trough: 3 * Rivaroxaban * Recurrence: 7 per 100 person-years * Major bleed: 7 per 100 person-years * peak-to-trough: 10 =====Other Options===== * Thrombolysis: not routinely performed * Indications (thrombolysis/thrombectomy) * phlegmasia cerulea dolens * massive iliofemoral DVT * failure of therapeutic anticoagulation * candidates: * symptoms < 14 days * good functional status * low bleeding risk