======Transfusion Reactions======

^  Reactions  ^  Description  ^  
| Benign febrile non-hemolytic transfusion reaction | Fever immediately |
| Acute hemolytic transfusion reaction | Fever immediately, followed by \\ Tachycardia, shock, flank pain, hemoglobinuria (muddy brown urine without RBCs) |
| Delayed Hemolytic Transfusion Reaction \\ Delayed Serologic Transfusion Reaction (no hemolysis) | Days to weeks \\ Jaundice, pallor, fatigue |
| IgE-mediated allergic reaction | Hives, urticaria, anaphylaxis |
| Transfusion-transmitted bloodstream infection |  |
| Graft versus Host Disease | |
| TACO | |
| TRALI | |
| Viral Transmission | |
| Iron Overload | |

=====Management=====
  * Concern for acute hemolytic transfusion reaction
    - Stop transfusion
    - Take care of patient (meds, fluids, oxygen)
    - Call blood bank
      - Peripheral smear
      - Direct/indirect Coombs
      - Other hemolysis labs

=====Other=====
  * All pRBCs are leukoreduced at LAC+USC
  * Preparing for Blood
    * Blood type: ABO/Rh status, <15 minutes (for lab)
    * Screen: 15-30 minutes (for lab)
    * Cross: 30-60 minutes (for lab), highly variable