| Drug class | Considerations | Preoperative management |
|---|---|---|
| Beta blockers | Withdrawal hypertension | Continue during surgery |
| Alpha 2 agonists | Withdrawal hypertension | Continue during surgery |
| Calcium channel blockers | Slight increased bleeding risk | Continue during surgery |
| ACE inhibitors | Hypotension | Continue during surgery for patients with heart failure Hold night prior for other patients (10 hours) |
| Diuretics | Hypovolemia and hypotension | Hold morning of surgery |
| Statins | Myopathy | Continue during surgery |
| SERMs | VTE | Stop 4 weeks prior |