Hepatitis B

Serologies

Test			Interpretation	Vaccination
HBsAg	HBsAb	HBc Ab	Interpretation	Vaccination
-	-	-	Susceptible	Vaccinate
-	+	-	Immunized	Not indicated
-	+	+	Immune due to natural infection	Not indicated
+	-	+ IgM +	Acutely infected	Not indicated
+	-	+ IgM -	Chronically infected	Not indicated
-	-	+	Equivocal	Clinical judgment

May be distantly immune, but the test may not be sensitive enough to detect a very low level of anti-HBs in serum
May be susceptible with a false positive anti-HBc
May be chronically infected and have an undetectable level of HBsAg present in the serum
May be passive transfer of anti-HBc to infant born to HBsAg-positive mother
May be recovering from acute HBV infection and detectable anti-HBs has not yet appeared